There are 3 rhythms that are irregularly irregular :
1. Sinus arrhythmia : one P wave morphology and a stable PR interval
2. Multifocal atrial rhythm   
    =  Wandering atrial pacemaker (rate <100 bpm)
    or Multifocal atrial tachycardia (MAT) (rate >100 bpm) : 
-  Multiple ectopic foci within the atria
-  Most commonly in seriously ill elderly with severe COPD or CHF
-  Typically a transitional rhythm
    between frequent APCs to atrial flutter / fibrillation
-  MAT during an acute illness is a poor prognostic sign
    associated with a 60% in-hospital mortality 
 
-  More than 3 forms of P wave morphologies
    without any one P wave morphology being dominant
    + Variable PR interval
 
- Some P waves may be nonconducted; others may be aberrantly conducted 
- Mechanism : 
   Right atrial dilatation (from cor pulmonale)
   Increased sympathetic drive
   Hypoxia and hypercarbia
   Beta-agonists
   Theophylline
   Electrolyte abnormalities :
   Hypokalaemia and hypomagnesaemia (e.g. secondary to diuretics / beta-agonists)
The net result is increased atrial automaticity.
 

 
3. Atrial fibrillation : no organized P waves seen
-   Haemodynamic instability, cardiomyopathy, cardiac failure, embolic events such as stroke.
-   Causes of atrial fibrillation :
     Ischaemic heart disease
     Hypertension
     Valvular heart disease (esp. mitral stenosis / regurgitation)
     Acute infections
     Electrolyte disturbance (hypokalaemia, hypomagnesaemia)
     Thyrotoxicosis
     Drugs (e.g. sympathomimetics)
     Pulmonary embolus
     Pericardial disease
     Acid-base disturbance
     Pre-excitation syndromes
     Cardiomyopathies: dilated, hypertrophic.
     Phaeochromocytoma
 
-   Commonly Af ventricular rate : 110 – 160
     RVR > 100, SVR < 60 
-   Causes of slow AF : hypothermia, digoxin toxicity, medications, sinus node dysfunction
-   Ashman's Phenomenon : presences of aberrantly conducted beats, usually of RBBB morphology
    突然夾雜單一跳 wide QRS, 不是 VPC 
 
 

Irregular wide QRS :
- Af + bbb
- Af + WPW
- VT / VF
 
VT - pulse or pulseless
或分成單型性 or 多型性
多型 : TdP ( with QT prolong ) or non TdP 
 
 
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