醫學筆記匯整 ED Notes

先分類病人是 亢進 or 抑制 (安眠藥, opioid, cholin)

Pupil dilated :  

• Sympathomimetics
• Anticholinergic
• Morphine withdrawl 
   

汗腺 : Sympathetic cholinergic neurons
Sympathetic postganglionic neurons typically secrete NE (Sympathetic adrenergic neurons)
however, the sympathetic postganglionic neurons that innervate sweat glands secrete ACh (Sympathetic cholinergic neurons)


 

有機磷 : 和AchE酵素產生共價結合, 使Ach無法被已磷酸化的酵素水解, 導致Ach堆積體內而產生毒性
所以有膽鹼症狀, 

有機磷中毒 : 血中 cholinesterase 會降低, 但 liver dysfunction, malnutrition 也會低

治療 : Atropine, PAM