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- 壓不掉 + 摸的到 : Vasculitis
Acute meningococcal, Gonococcal
- Purpura 紫斑:2~10 mm
- Henoch-Schönlein purpura
- ITP ( Idiopathic thrombocytopenic purpura )
- Gonococal
- Meningococcal
Age : 6M ~ 青少年 ( 75% < 10y/o )
Self limited 約 4-6 W
最常影響 :
- Skin : Palpable purpura
- Joint ( Knee, ankle ) : Arthralgia, Arthritis
- Kidney : IgA nephritis, Hematuria, HTN
通常在發病後1個月後
- GI tract : Abdominal pain ( Bowel angina, colicky ) 通常在 purpura 之後
N/V, GI bleeding,
Rare : Intussusception, GB 水腫
通常在 URI 後 ( Strept ) ( ASO titer )
- Serum IgA 上升
- Biopsy 出現 IgA immunocomplex ( )
- IgA rheumatoid factor
- ANCA
Clinical diagnosis :
- Age < 20
- Bowel angina
- Palpable purpura
- Biopsy
Workup :
- Lab
- UA
- Stool OB
- BP : HTN
- Biopsy
- ASO titer
- 要長期 f/u nephritis
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