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* Cardiomyopathy 定義 : 
   先排除因為 HTN, CAD, VHD or congenital heart disease
   等原因所造成的次發性心肌病變



e88cf01f-d12f-4eaa-9f53-2e1c0fd79005.png

cmps.gif
 

33c53b9d1813b873fbab45106457f69e.gif
 

 

8c6b43ed-f0f5-4cec-aab7-4dfe87999db6.png
 

DCM : 壁薄, 四腔室擴大 , Systolic dysfunction
 

HCM : 不對稱中膈肥厚 (中膈/後壁>1.3) 
              LV 變超小 
, Diastolic dysfunction
              Gene(AD), mitral valve SAM => LVOT obstruction
              beta blocker, CCB

 

RCM : 壁變硬,  Diastolic dysfunction, Infiltrative, Treat reason
 

*** SAM 示意圖 ***

7b9fe5cc-4dc7-4681-aa01-5cbfe42b8eb8.png

HOCM 特色 : 

1. Systolic anterior motion (SAM) of the mitral valve
    and dynamic left ventricular outflow tract (LVOT) obstruction
2. Asymmetrical thickening of the anterior interventricular septum
   (Asymmetrical septal hypertrophy)


 

76cba397-edd0-4ddc-9901-510d9e34cd16.png
 

  • DCM : CHF symptoms
  • HCM : Syncope, Sudden death
  • RCM : DOE, Fatigue 

 

4c589660-9606-4b55-85ab-ec3c26228946.png


* HCM EKG :

   - Deep, narrow (dagger-like)“Septal Q waves” in the lateral and sometimes inferior leads
     (Due to the abnormally hypertrophied interventricular septum)

     下壁 + 外側壁 --- > Q wave 

   - LVH

   - 大 R 波  lead T inv 

   - Sometimes associated with WPW
   - P mitrale (LAE) : Left ventricular diastolic dysfunction

 

hocm 2- pseudo q, less labelled.jpg

HCM :
 - Exertional syncope or pre-syncope
    suggesting dynamic LVOT obstruction ± ventricular dysrhythmia,
    with the potential for sudden cardiac death.
 - Symptoms of pulmonary congestion due to left ventricular dysfunction
   (exertional dyspnoea, fatigue, orthopnoea, paroxysmal nocturnal dyspnoea)
   
 - Chest pain may be typical anginal pain due to increased demand (thicker myocardial walls)
   and reduced supply (aberrant coronary arteries).

 - Palpitations due to supraventricular or ventricular arrhythmias.

 


* HCM : 

93cd64a9-504f-4bcc-94b2-0eb22bba8f79.png


* DCM : 

705f2099-0dfe-447d-ab1d-b4a94b386f42.png

 

* HCM Mamagement :
- Restriction of physical activity ( 只能輕度中度有氧運動 )
- Implantable cardioverter-defibrillators ( ICD )
Nonpharmacologictreatment of LVOT obstruction
- Medical treatment : Beta-blocker, CCB 
- Catheter ablation

 

11c8421d-1d84-4f68-b1d6-9a4363eafa81.png



* 水多水少?
    回心血流增加 : 蹲姿, 肌肉收縮, 吸氣 (胸內負壓增加->靜脈回流增加)
    回心血流減少 : 站姿, valsava maneuver, 吐氣

 

HCM 因為肌肉夾很緊, 回心血多肌肉被撐開 -> murmur 變小聲
血少 -> murmur 變大聲
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