醫學筆記匯整 ED Notes

UC 只在 Colon, 幾乎都有 Rectum
連續 lesion 

CD 全部 GI tract skip lesion
Terminal ileum 常被 involve
Rectum 侵犯少

• Abd pain
  Mucus containing
  Non grossly bloody diarrhea
  N/V, Bloating, Obstipation
   
• Extracolonic :
  Uveitis, Skin lesion, Arthritis, Chronic hepatitis, Thromboembolic events
  眼, 皮, 關節, 肝, 栓塞
   
• Non caseating granuloma
  deep & long fissure 導致切割出 Cobble stone
   
• Fibrosis, fistula, stricture, abcess
  因為侵犯的深所以 complication 多

• Grossly bloody diarrhea
  Lower abd cramps
  Urgency, Tenesmus
   
• Extracolonic :
  Uveitis, Skin lesion, Arthritis, Chronic hepatitis, Thromboembolic events
  眼, 皮, 關節, 肝, 栓塞
  外加 PSC !!

• Lesion 只在 Colon, Rectum involement 95%
• Continuous lesion, 只有 mucosa layer involve
• Diffuse ulceration, Crypt abcess, Pseudopolyps
   

IBD 傳統上已經有許多藥品, 包括 5-ASA,  類固醇

使用抗TNF單株抗體可能會增加感染風險
尤其是結核菌, 黴菌與伺機性細菌感染
因此使用這些藥品都必須追蹤感染症狀與病徵